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and introducing The Supplement Cabinet
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This week's issue of Feisty 40+ is presented by Previnex. Get 15% off your first order at previnex.com with the code FEISTY40PLUS.

🏋🏻‍♀️ Does Perimenopause Turn Down Your Power?


I remember the exact moment I noticed my power was off. It was the first day of the Titan Tropic Cuba, a six-day mountain bike stage race on the sub-tropical island. I was chasing the lead group, who had just swept through a right hand bend leading into a short steep kicker. I got out of the saddle and punched down on my pedals to pop up and over the top and there was decidedly no pop. It wasn’t exactly a fizzle. But perhaps more like a strong peep. 


I remember thinking, “Huh, that’s weird.” My next thought was, “Did I age overnight?” I was 47 at the time, and confess, I wasn’t really doing any real or consistent resistance training. I never really needed to. Or maybe I did and didn’t know it, which is what I’ve since discovered and a new study on sex hormones and female neuromuscular function across the lifespan suggests. 


Form Follows Function

We talk a lot about muscles here and how maintaining muscle mass is key to healthy aging. But muscle function matters too—especially for sports performance—and neuromuscular function is a major factor. Neuromuscular function is the interaction between your nervous system and your muscles. Efficient neuromuscular function allows for optimal muscle activation, coordination, and force production, which are essential for generating high levels of power–the ability to produce force quickly. Like, you know, punch it over a climb.


To determine how neuromuscular function changes across a woman’s lifespan, and examine the potential role of menopausal hormone changes, a team of researchers mapped neuromuscular function, body composition, lifestyle, diet, and primary sex hormone concentrations in 88 females ranging in age from 18 to 80.


In a nutshell, they found a non-linear and accelerated reduction in neuromuscular function that occurs during the fourth decade and coincides with menopause onset associated with changes in sex hormone concentrations. 


Specifically, the steepest declines in muscle strength, power, and torque occurred around ages 43 to 47, which aligns closely with perimenopause. The decline started before major muscle mass loss, which suggests that functional impairments precede structural muscle changes. Importantly, these declines occurred even after controlling for age, activity (the women in the study exercised about 44 minutes a day on average), and protein intake, suggesting sex hormones play a key role.


Optimal Muscle Activation

The researchers of this study concluded that: “Interventions aimed at mitigating declines in ovarian hormones and their subsequent effects on neuromuscular function after menopause should be further explored.”


That said, it’s important to note that they also found no significant associations between hormone replacement therapy or hormonal contraception with any of the neuromuscular outcomes. So, as with muscle mass, it’s not as simple as using hormone therapy.


So, what to do? Some loss of muscle mass and function is inevitable with age for everyone and with the menopause transition for women. It stands to reason that the more muscle you have and the more highly tuned your neuromuscular function, the better off you are in the long run. That means regular heavy and high intensity resistance training.


If I could go back and change one thing, I’d have gotten serious about regular strength training earlier. It’s the one thing I suggest everyone within earshot (or eyeshot) of me do.


When I got back from Cuba (where I finished just off the podium every day), I joined a CrossFit gym, learned to lift heavy, and started a practice of regular resistance and plyometric training. My power improved, my pop returned, and I achieved a few more podiums in the seasons that followed. More importantly, nine years later, I feel well-positioned to maintain power into my older years. And that’s what it’s all about.

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💊 The Supplement Cabinet


I get a lot of questions about supplements. So, after 64 weeks of Might It Be Menopause (which to be abundantly clear means we covered sixty four different symptoms), we’re going to give MIBM a little break and introduce The Supplement Cabinet to answer popular supplement questions. First up: Tart Cherry Juice. 


If you watch pro cycling (and it is Tour de France month), you’ll have noticed that a lot of pros are slugging down a bottle of ruby red juice as soon as they cross the finish line. That’s tart cherry juice, which is brimming with antioxidants like anthocyanins, and research finds that it can accelerate muscle recovery, lower markers of inflammation, and reduce DOMS (delayed onset muscle soreness).


Tart cherry juice also has been shown to improve sleep in 50+ aged women, as it helps with melatonin production.


On Hit Play Not Pause (episode 208), exercise physiologist and certified sports nutritionist Alyssa Olenick, PhD, called tart cherry juice her “luteal phase and menopause go-to” for women who need extra sleep and recovery support during those times. 


The pros drink it right after hard sessions and before bed. The most common dosage is either 30 mL of tart cherry juice concentrate or 237 mL of tart cherry juice, consumed twice per day, according to Examine.com. The juice appears to work best when you use it regularly















🔥 Feisty Badass Athlete of the Week Goes To…


Put your hands together for Leonie Hilsdon, 54, who after going through hell with menopause-related anxiety, full body joint aches, insulin resistance, and body composition changes, along with illness, injuries, and personal strife, lined up for a triathlon after 30 years away from the sport. 


It was hot (27C/80F) and there were headwinds, but she finished, and as she said in her post “I am still buzzing.” And not only that — she's going back for more. Leonie has signed up for another one eight weeks out. Way to overcome, Leonie. We’ll be cheering for you!
















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👩🏻‍💻 Hit Play Research Round Up

We spend a lot of time scouring the latest research for news you can use to stay strong and feisty forever. Here’s what’s making waves this week:


🏋🏻‍♀️ Heavy lifting can significantly enhance performance in endurance cyclists, according to a new systematic review with meta-analysis. That’s because heavy resistance training doesn’t just make you stronger, it allows you to use your muscles more economically by enhancing muscular coordination and timing, improving pedalstroke mechanics, and delaying the recruitment of less efficient fast-twitch muscle fibers. It also improves your anaerobic power, so you can surge, recover, and finish stronger.


🏃🏾‍♀️ Follow the 10% rule to avoid injury. It’s conventional wisdom that you should increase your weekly training load by no more than 10%. Now, a study of more than 5,200 runners shows that the biggest injury risk happens when we make big jumps in a single session. Runners who increased their distance in a single session by more than 10% compared to their longest run in the past 30 days had a significantly higher risk of overuse injuries. 


Here’s how spikes in a single session increased risk:

Small spike (↑10–30%) → 64% higher risk
Moderate spike (↑30–100%) → 52% higher risk
Large spike (↑>100%) → 128% higher risk 


Bottom line: Avoid big jumps in distance within a single session—even if your weekly volume looks okay.


💊 Do you need to change your prescription drug doses when you hit menopause? That’s a very interesting question raised by an article in BMC Medicine. Hormone changes during menopause–particularly the steep drop in estrogen–can influence how drugs are absorbed, metabolized (especially via liver enzymes like CYP3A4 and CYP1A2), and excreted. These changes could contribute to reduced efficacy or increased side effects in midlife women, but we need more research to know for sure. In the meantime, if you notice changes in how your drugs are working or making you feel, bring it up with your doctor.










What's On My Mind...


A new study published in Menopause showing that women get better at managing their anger with age (both chronologic and reproductive) made a bunch of headlines a couple of weeks ago. To me it’s just more evidence that we just start giving far less f***s and don’t waste our energy (or anger) on the small stuff any longer. I’m glad they’re researching menopause, but I, for one, don't need a study to tell me that.


🎧 Listen to this week's episode of Hit Play Not Pause - Outrunning Assumptions: How to Get Faster in Midlife and Menopause with Jen Temperley


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Feisty 40+ is written by Selene Yeager. Edited by Maya Smith. Ads by Ella Hnatyshyn


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